660 Bone marrow coagulated and low-level laser therapy accelerate bone healing

660 Bone marrow coagulated and low-level laser therapy accelerate bone healing

Study Overview

  • Description: The present study evaluated the effects of bone marrow aspirate (BMA) and low-level laser therapy (LLLT) on bone healing.
  • Source: PubMed 

Summary

  • Participants: 64 rats, with critical-size defects (CSD) of 5 mm diameter created in their calvaria.
  • Groups: Animals were randomly divided into four groups:Control: Blood clot only.BMA: Coagulated bone marrow aspirate.LLLT: Laser irradiation and blood clot.BMA/LLLT: Laser irradiation and coagulated bone marrow aspirate.
  • Control: Blood clot only.
  • BMA: Coagulated bone marrow aspirate.
  • LLLT: Laser irradiation and blood clot.
  • BMA/LLLT: Laser irradiation and coagulated bone marrow aspirate.
  • Intervention: Euthanasia was performed at 15 or 30 days postoperative.
  • Findings (Based on Title and Abstract Snippet): Bone marrow coagulate and low-level laser therapy accelerate bone healing by enhancing angiogenesis, cell proliferation, osteoblast differentiation, and mineralization.