660 Bone marrow coagulated and low-level laser therapy accelerate bone healing
Study Overview
- Description: The present study evaluated the effects of bone marrow aspirate (BMA) and low-level laser therapy (LLLT) on bone healing.
- Source: PubMed
Summary
- Participants: 64 rats, with critical-size defects (CSD) of 5 mm diameter created in their calvaria.
- Groups: Animals were randomly divided into four groups:Control: Blood clot only.BMA: Coagulated bone marrow aspirate.LLLT: Laser irradiation and blood clot.BMA/LLLT: Laser irradiation and coagulated bone marrow aspirate.
- Control: Blood clot only.
- BMA: Coagulated bone marrow aspirate.
- LLLT: Laser irradiation and blood clot.
- BMA/LLLT: Laser irradiation and coagulated bone marrow aspirate.
- Intervention: Euthanasia was performed at 15 or 30 days postoperative.
- Findings (Based on Title and Abstract Snippet): Bone marrow coagulate and low-level laser therapy accelerate bone healing by enhancing angiogenesis, cell proliferation, osteoblast differentiation, and mineralization.